Skip to product information
1 of 4

Skinceuticals

SkinCeuticals Discoloration Defense | Targeted Serum for Dark Spots & Uneven Skin Tone

SkinCeuticals Discoloration Defense | Targeted Serum for Dark Spots & Uneven Skin Tone

Regular price $85.10 USD
Regular price $115.00 USD Sale price $85.10 USD
Sale Sold out
Shipping calculated at checkout.

Clinical Dark Spot Corrector for Brighter, More Even Skin

SkinCeuticals Discoloration Defense is a daily-use, layerable corrective serum clinically proven to reduce visible skin discoloration and improve overall brightness. This advanced formula targets stubborn dark spots, post-acne marks, and uneven tone using a powerful combination of tranexamic acid, kojic acid, niacinamide, and HEPES—delivering visible results in as little as two weeks.

Skin Type

Dry · Normal · Oily · Combination

Skin Concern

Discoloration · Dark Spots · Post-Acne Marks · Uneven Skin Tone

Product Details

This next-generation brightening serum addresses multiple pathways of pigmentation to visibly reduce discoloration and help prevent future recurrence with continued use. Clinically shown to deliver up to a 60% average improvement in stubborn brown patches, Discoloration Defense enhances skin clarity while supporting a smoother, more even complexion.

Designed to complement professional treatments such as chemical peels and non-ablative laser procedures, this serum provides ongoing at-home correction for long-term tone refinement.

How to Use

  • Apply 3–5 drops to clean, dry skin twice daily.

  • In the morning, apply after a SkinCeuticals vitamin C antioxidant serum and follow with a broad-spectrum SPF 50+ sunscreen.

  • In the evening, apply before moisturizer.

  • Limit sun exposure while using this product.

  • Do not apply to irritated or broken skin. Discontinue use if irritation occurs.

Experience Professional Results

For brighter, more even skin tone, experience SkinCeuticals Discoloration Defense as part of a customized discoloration-correction regimen at The Treatment Skin Boutique.
Our expert providers frequently pair this serum with in-office treatments to accelerate results and maintain long-term skin clarity.

Book your in-person appointment today.

Key Ingredients

3% Tranexamic Acid – Targets visible discoloration and helps prevent recurrence.
1% Kojic Acid – Improves the appearance of uneven pigmentation.
5% Niacinamide – Strengthens the skin barrier and enhances tone uniformity.
5% HEPES – Promotes gentle exfoliation and improved radiance.

View full details